Publikationen

 

Wissenschaftliche Veröffentlichungen

2017, 2016, 2015, 2014, 2013, 2012, 20112010, 2009, 2008, 2007, 2006, 2005, 2004, Ältere Publikationen

2017

179. Silver Oxide Mediated Monotosylation of Poly(ethylene glycol): Heterobifunctional PEG via Polymer Desymmetrization
      
H. Pohlit, M. Worm, J. Langhanki, E. Berger-Nicoletti, T. Opatz, H. Frey, Macromolecules 2017, accepted.

178. Oxidation of Trialkylamines by BrCCl3—Scope, Applications and Mechanistic Aspects
      
A. M. Nauth, J. C. Orejarena Pacheco, S. Pusch, T. Opatz, Eur. J. Org. Chem. 2017, accepted.

177. Polyethylene bio-degradation by caterpillars?
   
C. Weber, S. Pusch, T. Opatz, Curr. Biol. 2017, 27, R744-R745.

176. Phytotoxic dioxolanones are potential virulence factors in the infection process of Guignardia bidwellii
   I. Buckel, L. Andernach, A. Schüffler, M. Piepenbring, T. Opatz, E. Thines, Sci. Rep. 2017, 7, 8926.

175. Examples of Xylochemistry: Colorants and Polymers
   J. Kühlborn, A.-K. Danner, H. Frey, R. Iyer, A. J. Arduengo III, T. Opatz, Green Chem. 2017, 19, 3780–3786.

174. A New Member of the Fusaricidin Family – Structure Elucidation and Synthesis of Fusaricidin E
   M. Reimann, L. P. Sandjo, L Antelo, E. Thines, I. Siepe, T. Opatz, Beilstein J. Org. Chem. 2017, 13, 1430–1438.

173. Modular De Novo Synthesis of Unsymmetrical BODIPY Dyes possessing four different Aryl Substituents
   
N. Netz, C. Díez-Poza, A. Barbero, T. Opatz, Eur. J. Org. Chem. 2017, 4580–4599.

172. Cytotoxicity of Secondary Metabolites from Dracaena viridiflora Engl & Krause and their Semisynthetic Analogues
   
R. B. Teponno, J. P. Dzoyem, R. N. Nono, U. Kauhl, L. P. Sandjo, L. A. Tapondjou, U. Bakowsky, T. Opatz, Rec. Nat. Prod. 2017, 11, 421–430.

171. Photo-Chromium: Sensitizer for Visible Light-Induced Oxidative C-H Bond Functionalization – Electron or Energy Transfer?
  
S. Otto, A. M. Nauth, E. Ermilov, N. Scholz, A. Friedrich, U. Resch-Genger, S. Lochbrunner, T. Opatz, K. Heinze, ChemPhotoChem 2017, 1, 344–349.
Cover picture of Issue 8.

170. The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through the KEAP1-NRF2/HO-1 pathway
   
C. Hong, J. Cao, C.-F. Wu, O. Kadioglu, A. Schüffler, U. Kauhl, S. M. Klauck, T. Opatz, E. Thines, T. Efferth, Sci. Rep. 2017, 7, 11551.

169. New Photochemical Approaches to the Bilobalide Core
   
J. Emsermann, T. Opatz, Eur. J. Org. Chem. 2017, 3362–3372.

168. Light-Induced Alkylation of (Hetero)aromatic Nitriles in a Transition Metal-Free C–C-Bond Metathesis
   
B. Lipp, A. Lipp, H. Detert, T. Opatz, Org. Lett2017, 19, 2054–2057.

167. Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibiton by the Chinese Herbal Remedy Free and Easy Wanderer
   
C. Hong, A. Schüffler, U. Kauhl, J. Cao, C.-F. Wu, T. Opatz, E. Thines, T. Efferth, Front. Pharmacol2017, 8, 181.

166. “Clickable PEG” via anionic copolymerization of ethylene oxide and glycidyl propargyl ether
    J. Herzberger, D. Leibig, J. Langhanki, C. Moers, T. Opatz, H. Frey, Polym. Chem. 2017, 8, 1882–1887.

165. Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7)
    I. Hellmuth, I. Freund, J. Schlöder, S. Seidu-Larry, K. Thüring, K. Slama, J. Langhanki, S. Kaloyanova, T. Eigenbrod, M. Krumb, S. Röhm, K. Peneva, T. Opatz, H. Jonuleit, A. H. Dalpke, M. Helm, Front. Immunol. 2017, 8, 312.

164. Synthesis and Biological Evaluation of a D-Ring-contracted Analogue of Lamellarin D
       V. Colligs, S. P. Hansen, D. Imbri, E.-J. Seo, O. Kadioglu, T. Efferth, T. Opatz, Bioorg. Med. Chem. 2017, im Druck.

163. An Asymmetric One-Pot Synthesis of (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol: A Key Component of Current HIV Protease Inhibitors
       A. Sevenich, G.-Q. Liu, A. J. Arduengo III, B. F. Gupton, T. Opatz, J. Org. Chem. 201782, 1218–1223.
Article was highlighted in: Synfacts 2017, 13, 0335.

162. A Modular Access to (+/-)-Tubocurine and (+/-)-Curine - Formal Total Synthesis of Tubocurarine
       N. Otto, D. Ferenc, T. Opatz, J. Org. Chem. 201782, 1205–1217.

161. Sunflow: Sunlight Drives Fast and Green Photochemical Flow Reactions in Simple Micro Capillary Reactors — Application to Photoredox- and H-Atom Transfer Chemistry
       A. M. Nauth, A. Lipp, B. Lipp, T. Opatz, Eur. J. Org. Chem. 2017, 2099–2103.
Link to Video Abstract.

160. Synthesis of Piperidines and Dehydropiperidines: Construction of the Six-Membered Ring
       M. M. Nebe, T. Opatz, Adv. Heterocycl. Chem. 2017, 122191–244.

159. Haloperoxidase mimicry by CeO2-x nanorods combats biofouling
       K. Herget. P. Hubach, S. Pusch, P. Deglmann, H. Götz, T. E. Gorelik, I. A. Gural'skiy, F. Pfitzner, T. Link, S. Schenk, M. Panthöfer, V. Ksenofontov, U. Kolb, T. Opatz, R. André, W. Tremel
       Adv. Mater. 201729, 1603823.

158. ESI-MS2 and anti-inflammatory studies of cyclopropanic triterpenes. UPLC-ESI-MS and MS2 search of related metabolites
       from
Donella ubanguiensis
      
L. P. Sandjo, M. V. P. dos Santos Nascimento, L. A. L. da Silva, A. C. M. Munhoz, L. A. E. Pollo, M. W. Biavatti, B. T. Ngadjui, T. Opatz, T. S. Fröde
       Phytochem. Anal. 2017, 28, 27–41.

157. Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae
       Stefan Jacob; Thomas Grötsch; Andrew J. Foster; Anja Schüffler; Patrick H. Rieger; Louis P. Sandjo; Johannes C. Liermann; Till Opatz; Eckhard Thines
       Microbiology 2017, 163, 541–553.

 

2016

156. Characterization of the synthetic cannabinoid MDMB-CHMCZCA
      
Carina Weber, Stefan Pusch, Dieter Schollmeyer, Sascha Münster-Müller, Michael Pütz and Till Opatz
       Beilstein J. Org. Chem. 2016, 12, 2808–2815.

155. Anti-inflammatory Tetraquinane Diterpenoids from a Crinipellis species
       Markus Rohr, Katharina Oleinikov, Mathias Jung, Louis P. Sandjo, Till Opatz, Gerhard Erkel
       Bioorg. Med. Chem. 2016, 25, 514–522.

154. Absolute Configuration Determination of 2,3-Dihydro-1H,5H-pyrazolo-[1,2-a]pyrazoles using Chiroptical Methods at Different Wavelengths.
       Eva Pušavec Kirar, Uroš Grošelj, Amalija Golobič, Franc Požgan, Stefan Pusch, Carina Weber, Lars Andernach, Bogdan Štefane, Till Opatz, Jurij Svete
       J. Org. Chem. 2016, 81, 11802–11812.

153. Terphenyl Derivatives from Allantophomopsis lycopodina
       Andernach, Lars; Sandjo, Louis; Liermann, Johannes; Schlämann, Ricardo; Richter, Christian; Ferner, Jan-Peter; Schwalbe, Harald; Schueffler, Anja; Thines, Eckhard; Opatz, Till
       J. Nat. Prod. 2016, 79, 2718–2725.

152. Transition Metal-free Decarboxylative Photoredox Coupling of Carboxylic Acids and Alcohols with Aromatic Nitriles
       B. Lipp, A. M. Nauth, T. Opatz
       J. Org. Chem. 2016, 81, 6875-6882.

151. A Short and Modular Approach towards 3,5-Disubstituted Indolizidine Alkaloids
      
M. M. Nebe, S. Zinn, T. Opatz
       Org. Biomol. Chem. 2016, 14, 7084-7091.

150. Total Synthesis of Phenanthroindolizidine Alkaloids by Combining Iodoaminocyclization with a Free Radical Cyclization
      
G.-Q. Liu, M. Reimann, T. Opatz
       J. Org. Chem. 2016, 81, 6142-6148.

149. Secondary brown carbon formation via the dicarbonyl imine pathway: Nitrogen heterocycle formation and synergistic effects
    
   C. J. Kampf, A. Filippi, C. Zuth, T. Hoffmann, T. Opatz
       Phys. Chem. Chem. Phys. 2016, 18, 18353-18364.

148. A Light-Induced Vinylogous Nazarov-Type Cyclization
      
S. Pusch, D. Schollmeyer, T. Opatz
       Org. Lett. 2016, 18, 3043-3045.

147. Separation, isolation and stereochemical assignment of imazalil enantiomers and their quantitation in an in vitro toxicity test
      
M. Escolà Casas, A. C. Kretschmann, L. Andernach, T. Opatz, K. Bester
       J. Chromatogr. A 2016, 1452, 116-120.

146. Light Induced C–C Coupling of 2-Chlorobenzazoles with Carbamates, Alcohols, and Ethers
      
A. Lipp, G. Lahm, T. Opatz
       J. Org. Chem. 2016, 81, 4890-4897.

145. Absolute configuration of the synthetic cannabinoid MDMB-CHMICA with its
       chemical characteristics in illegal products
      
L. Andernach, S. Pusch, C. Weber, D. Schollmeyer, S. Münster-Müller, M. Pütz, T. Opatz.
       Forensic Toxicol. 2016, 34, 344-352.

144. 3,4-Dihydro-2H-pyrrole-2-carbonitriles – Useful Intermediates in the Synthesis of Fused Pyrroles
       and 2,2’-Bipyrroles
      
M. M. Nebe, M. Kücükdisli, T. Opatz
       J. Org. Chem 2016, 81, 4112-4121.

143. A Photoinduced Cobalt-Catalyzed Synthesis of Pyrroles through In-Situ Generated Acylazirines
      
S. Pusch, D. Kowalczyk, T. Opatz
       J. Org. Chem. 2016, 81, 4170-4178.

142. A Surprising Switch in Absolute Configuration of Anti-Inflammatory Macrolactones
      
J. Tauber, M. Rohr, T. Walter, D. Schollmeyer, K. Rahn-Hotze, G. Erkel, T. Opatz
       Org. Biomol. Chem. 2016, 14, 3695-3698.

141. A Short Synthesis of Pyridines from Deprotonated α-Aminonitriles by an Alkylation/RCM Sequence
      
C. Weber, M. M. Nebe, L. P. V. Kaluza, T. Opatz
       Z. Naturforsch. B 2016, 71, 633-641.

140. Antifungal Paenibacillus Strains, Fusaricidin-Type Compounds, and their Use.
      
I. Siepe, H. Brüser, K. Klappach, K.-H. Schneider, P. Spröte, K. Hage, B. Blanz, E. Thines, L. Antelo, L. P. Sandjo, T. Opatz
       PCT Int. Appl. 2016, WO2016020371.  

139. Synthesis of 1,2-Disubstituted Indoles from α-Aminonitriles and 2-Halobenzyl Halides
      
A.-K. Bachon, T. Opatz
       J. Org. Chem. 2016, 81, 1858-1869.    

138. A Modular Formal Total Synthesis of (±)-Cycloclavine
      
N. Netz, T. Opatz
       J. Org. Chem 2016, 81, 1723-1730.

137. A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light:
       Application to the Synthesis of Tetraponerines and Crispine A
      
J. C. Orejarena Pacheco, A. Lipp, A. M. Nauth, F. Acke, J.-P. Dietz, T. Opatz
       Chem. Eur. J. 2016, 22, 5409-5415.  

136. Marine Isonitriles and Their Related Compounds
      
J. Emsermann, U. Kauhl, T. Opatz
       Marine Drugs 2016, 14, 16.

135. A Short Synthesis of 2,3,5-Trisubstituted Pyrroles by an Alkylation/Dehydrocyanation Sequence
       M. Kücükdisli, M. M. Nebe, S. M. Bartelt, T. Opatz
       Heterocycles 2016, 93, 378–390.

134. Total Synthesis of (–)-Hymenosetin
       
U. Kauhl, L. Andernach, S. Weck, L. Sandjo, S. Jacob, E. Thines, T. Opatz
        J. Org. Chem. 2016, 81, 215-228.
        Synfacts 2016, 12, 224.      

133. Total Synthesis of (±)-Scopolamine: Challenges of the Tropane Ring
       P.-A. Nocquet, T. Opatz
       Eur. J. Org. Chem. 2016, 1156-1164.

 

 

2015


132. Selective C–H-Activation of Methoxy Groups in a Three-Component Photoreaction
      
G. Lahm, T. Opatz
       J. Org. Chem. 2015, 80, 12711-12717.

131. Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells
      
M. Saeed, S. Jacob, L. Sandjo, Y. Sugimoto, H. Khalid, T. Opatz, E. Thines, T. Efferth
       Front. Pharmacol. 2015, 6, 267.

130. Synthesis of Lamellarin D Trimethyl Ether and Lamellarin H via 6π-Electrocyclization
      
C. Dialer, D. Imbri, S. Hansen, T. Opatz
       J. Org. Chem. 2015, 80, 11605-11610.
 
129. α-Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non-toxic Cyanide Source
      
A. M. Nauth, N. Otto, T. Opatz
       Adv. Synth. Catal. 2015, 357, 3424-3428.

128. Xylochemistry - Making Natural Products Entirely from Wood
      
D. Stubba, G. Lahm, M. Geffe, J. W. Runyon, A. J. Arduengo III, T. Opatz
       Angew. Chem. 2015, 127, 14394-14396 (Titelbild).
       Angew. Chem. Int. Ed. 2015, 54, 14187-14189 (Cover Picture).

127. Carbohydrate nanocarriers in biomedical applications: functionalization and construction
      
B. Kang, T. Opatz, K. Landfester, F. R. Wurm
       Chem. Soc. Rev. 2015, 44, 8301-8325.

126. Marine Indole Alkaloids
      
N. Netz, T. Opatz
       Mar. Drugs 2015, 13, 4814-4915.

125. Total Synthesis of two Potent Anti-Inflammatory Macrolactones of the Oxacyclododecindione Type
      
J. Tauber, M. Rohr, T. Walter, G. Erkel, T. Opatz
       Org. Biomol. Chem. 2015, 13, 7813-7821.

124. Antifungal Penicillium strains, fungicidal extrolites thereof, and their use
       
I. Siepe, T. Jabs, A. Schüffler, E. Thines, H. Anke, T. Opatz, L. P. Sandjo
       PCT Int. Appl. 2015, WO 2015067800.

123. Enantioselective Synthesis of α-Quaternary Amino Acids by Alkylation of Deprotonated α-Aminonitriles
      
I. Netz, M. Kücükdisli, T. Opatz
       J. Org. Chem. 2015, 80, 6864-6869.

122. Synthesis and Isolation of Enantiomerically Enriched Cyclopenta[b]benzofurans based on Products from Anodic Oxidation of 2,4-Dimethylphenol
      
M. Mirion, L. Andernach, C. Stobe, J. Barjau, D. Schollmeyer, T. Opatz, A. Lützen, S. R. Waldvogel
       Eur. J. Org. Chem. 2015, 4876-4882.

121. Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona
      
B. Kang, P. Okwieka, S. Schöttler, S. Winzen, J. Langhanki, K. Mohr, T. Opatz, V. Mailänder, K. Landfester, F. R. Wurm
       Angew. Chem. 2015, 127, 7544-7548.
       Angew. Chem. Int. Ed. 2015, 54, 7436-7440.         

120. Synthetic Approaches to Anti-Inflammatory Macrolactones of the Oxacyclododecindione Type
      
J. Tauber, K. Rudolph, M. Rohr, G. Erkel, T. Opatz
       Eur. J. Org. Chem. 2015, 3587-3608.

119. Synthesis of (−)-Cryptopleurine by Combining Gold(I)-Catalysis with a Free Radical Cyclization
      
A. Stoye, T. Opatz
       Eur. J. Org. Chem. 2015, 2149-2156.    

118. A One-Pot Cascade to Protoberberine Alkaloids via Stevens-Rearrangement of Nitrile-stabilized Ammonium Ylides
      
G. Lahm, J-G. Deichmann, A. Rauen, T. Opatz
       J. Org. Chem. 2015, 80, 2010-2016.

117. 4-Dechloro-14-deoxy-oxacyclododecindione and 14-Deoxy-oxacylododecindione, two Inhibitors of
       Inducible Connective Tissue Growth Factor Expression from the Imperfect Fungus Exserohilum rostratum

       J. Richter, L. P. Sandjo, J. C. Liermann, T. Opatz, G. Erkel
       Bioorg. Med. Chem. 2015, 23, 556-563.

116. 2-Aminoacetonitrile
       J. Tauber, T. Opatz
       Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2015, DOI: 10.1002/047084289X.rn01752.

 

 

2014 

 
115. Synthetic Approaches to the Lamellarins - A Comprehensive Review
      
D. Imbri, J. Tauber, T. Opatz
       Mar. Drugs 2014, 12, 6142-6177.

114. One-pot Synthesis of Pyrrole-2-carboxylates and -carboxamides via an Electrocyclization/Oxidation Sequence
      
D. Imbri, N. Netz, M. Kücükdisli, L. Kammer, P. Jung, A. Kretzschmann, T. Opatz
       J. Org. Chem. 2014, 79, 11750-11758.

113. Total Synthesis and Biological Evaluation of the Natural Product (–)-Cyclonerodiol, a New Inhibitor of IL-4 Signaling
      
J. Langhanki, K. Rudolph, G. Erkel, T. Opatz
       Org. Biomol. Chem. 2014, 12, 9707-9715.

112. Total Synthesis of Oxalicumone C and Elucidation of its Absolute Configuration
      
C. Wink, L. Andernach, T. Opatz, S. R. Waldvogel
       Eur. J. Org. Chem. 2014, 7788-7792.

111. A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
      
S. Pusch, T. Opatz
       Org. Lett. 2014, 16, 5430-5433.

110. Radical Addition to Iminium Ions and Cationic Heterocycles
      
J. Tauber, D. Imbri, T. Opatz
       Molecules 2014, 19, 16190-16222.

109. Enantioselective Synthesis of (–)-Dihydrocodeine and Formal Synthesis of
       (–)-Thebaine, (–)-Codeine, and (–)-Morphine from a Deprotonated α-Aminonitrile
      
M. Geffe, T. Opatz
       Org. Lett. 2014, 16, 5282-5285.

108. Fungicidal naphthoquinones and derivates
      
C. Wiebe, J. Reinheimer, D. Kremzow-Graw, F. Roehl, S. Schwolow, T. Opatz, A. Schueffler, H. Kunz, E. Thines
       PCT Int. Appl. 2014, WO 2014118099.

107. Heterocycles from α-Aminonitriles (Concept article)
       N. Otto, T. Opatz
       Chem. Eur. J. 2014, 20, 13064-13077.   

106. Unique Regioselectivity in the C(sp3)–H α-Alkylation of Amines:
       The Benzoxazole Moiety as a Removable Directing Group
      
G. Lahm, T. Opatz
       Org. Lett 2014, 16, 4201-4203.

105. Excelsoside: A new Benzylic Diglycoside from the Leaves of Milicia excelsa
      
J. L. N. Ouete, L. P. Sandjo, D. W. F. G. Kapche, S. O. Yeboah, R. Mapitse, B. M. Abegaz, T. Opatz, B. T. Ngadjui
       Z. Naturforsch. C 2014, 69, 271-275.    

104. A Two-step Synthesis of 2-Aminoindolizines from 2-Alkylpyridines
      
M. Kücükdisli, T. Opatz
       Eur. J. Org. Chem. 2014, 5836-5844.

103. Rearrangements of Nitrile-stabilized Ammonium Ylides
      
G. Lahm, J. C. Orejarena Pacheco, T. Opatz
       Synthesis 2014, 46, 2413-2421.

102. Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)
      
L. P. Sandjo, C. G. Fru, V. Kuete, F. Nana, S. O. Yeboah, R. Mapitse, B. M. Abegaz, T. Efferth, T. Opatz
       Z. Naturforsch. C 2014, 69, 276-282.

101. Assignment of the Absolute Configuration and Total Synthesis of (+)-Caripyrin
      
L. Andernach, T. Opatz
       Eur. J. Org. Chem. 2014, 22, 4780-4784.

100. Ring Expansion of 1,2,3,4-Tetrahydroisoquinolines to Dibenz[c,f]azonines. An Unexpected
       [1,4]-Sigmatropic Rearrangement of Nitrile-Stabilized Ammonium Ylides.
      
J. C. Orejarena Pacheco, T. Opatz
       J. Org. Chem. 2014, 79, 5182-5192.

99. Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species
     
S. Felix, L. P. Sandjo, T. Opatz, G. Erkel
      Bioorg. Med. Chem. 2014, 22, 2912-2918.

98. Zugänge zu Isomeren und Verwandten der Lamellarin-Alkaloide
     
J. Tauber, D. Imbri, V. C. Colligs, T. Opatz
      Z. Naturforsch. B 2014, 69, 627-640. 

97. Chemoenzymatic Synthesis of Functional Sialyl Lewisx-Mimetics with a Heteroaromatic Core
     
C. Schlemmer, C. Wiebe, D. Ferenc, D. Kowalczyk, S. Wedepohl, P. Ziegelmüller, J. Dernedde, T. Opatz
      Chem. Asian J. 2014, 9, 2119-2125.

96. Chromatographically Separable Rotamers of an Unhindered Amide
     
M. Geffe, L. Andernach, O. Trapp, T. Opatz
      Beilstein J. Org. Chem. 2014, 10, 701-706.

95. Simple Two-Step Synthesis of 2,4-Disubstituted Pyrroles and 3,5-Disubstituted Pyrrole-2-carbonitriles from Enones
     
M. Kücükdisli, D. Ferenc, M. Heinz, C. Wiebe, T. Opatz
      Beilstein J. Org. Chem. 2014, 10, 466-470.

94. Tanzawaic acids I-L: Four New Polyketides from Penicillium sp. IBWF104-06
     
L. P. Sandjo, E. Thines, T. Opatz, A. Schüffler
      Beilstein J. Org. Chem. 2014, 10, 251-258.

93. Synthetic approaches towards huperzine A and B 
     
S. M. A. Sohel, T. Opatz
      Arkivoc 2014 (i), 92-108.

 

2013

 


92. SF002-96-1, a New Drimane Sesquiterpene Lactone from an Aspergillus Species, Inhibits Survivin Expression
     
S. Felix, L. P. Sandjo, T. Opatz, G. Erkel
      Beilstein J. Org. Chem. 2013, 9, 2866-2876.
    
91. A High Yielding Modular Access to the Lamellarins: Synthesis of Lamellarin G
      Trimethylether, Lamellarin η and Dihydrolamellarin η
     
D. Imbri, J. Tauber, T. Opatz
      Chem. Eur. J. 2013, 19, 15080-15083.

90. New tracer compounds for secondary organic aerosol formation from β-caryophyllene
      oxidation
     
A. van Eijck, T. Opatz, D. Taraborrelli, R. Sander, T. Hoffmann
      Atmos. Environ. 2013, 80, 122-130.

89. Omphalocarpoidone, a New Lanostane-type Furano-spiro-γ-Lactone from the wood of 
      Tridesmostemon omphalocarpoides Engl. (Sapotaceae)
     
C. G. Fru, L. P. Sandjo, V. Kuete, J. C. Liermann, D. Schollmeyer, T. Opatz, B. T. Ngadjui
      Phytochem. Lett. 2013, 6, 676-680.

88. Total Synthesis of the Antifungal Natural Product Mollisin
     
S. Schwolow, H. Kunz, J. Rheinheimer, T. Opatz
      Eur. J. Org. Chem. 2013, 6519-6524.

87. A New Flavone from the Roots of Milicia excelsa (Moraceae)
     
J. L. Nantchouang Ouete, L. P. Sandjo, D. W. F. G. Kapche, J. C. Liermann, T. Opatz, I. K. Simo,
      B. T. Ngadjui
      Z. Naturforsch. C 2013, 68, 259-263.

86. One-Pot Synthesis of Polysubstituted Indolizines by an Addition/Cycloaromatization
      Sequence
     
M. Kücükdisli, T. Opatz
      J. Org. Chem. 2013, 78 (13), 6670-6676.

85. Configurational Assignment of a Series of Dioxolane-Type Secondary Metabolites
      from Guignardia bidwellii - A comparison of VCD and ECD Spectroscopy
     
L. Andernach, L. P. Sandjo, J. C. Liermann, I. Buckel, E. Thines, T. Opatz
      Eur. J. Org. Chem. 2013, 5946-5951.

84. Total Synthesis of (+)-Phenguignardic Acid, A Phytotoxic Metabolite of Guignardia
      bidwellii
     
A. Stoye, D. Kowalczyk, T. Opatz
      Eur. J. Org. Chem. 2013, 5952-5960.

83. Synthesis of Highly Substituted 2-13C-Imidazolium Salts and Metal NHC Complexes
      for the Investigation of Electronic Unsymmetry by NMR
     
J. Emsermann, A. J. Arduengo III, T. Opatz
      Synthesis 2013, 45, 2251-2264.

82. Synthesis of Alkaloids by Stevens Rearrangement of Nitrile-Stabilized Ammonium
      Ylides: (±)-Laudanosine, (±)-Laudanidine, (±)-Armepavine,
      (±)-7-Methoxycryptopleurine, and (±)-Xylopinine
     
J. C. Orejarena Pacheco, G. Lahm, T. Opatz
      J. Org. Chem. 2013, 78 (10), 4985-4992.

81. Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii
     
I. Buckel, D. Molitor, J. C. Liermann, L. P. Sandjo, B. Berkelmann-Löhnertz, T. Opatz, E. Thines
      Phytochemistry 2013, 89, 96-103.

80. Left, Right, or Both? On the Configuration of the Phenanthroindolizidine Alkaloid
      Tylophorine from Tylophora indica

      A. Stoye, T. E. Peez, T. Opatz
      J. Nat. Prod. 2013, 76 (2), 275-278.

 

2012
 

 

 

 

 

79. The Iodocyclization of o-Alkynylbenzamides Revisited: Formation of
      Isobenzofuran-1(3H)-imines and 1H-Isochromen-1-imines instead of Lactams
     
C. Schlemmer, L. Andernach, D. Schollmeyer, B. F. Straub, T. Opatz
      J. Org. Chem. 2012, 77, 10118-10124.

78. Drimane sesquiterpenoids from Marasmius sp. inhibiting the conidial
      germination of plant-pathogenic fungi
     
J. Liermann, E. Thines, T. Opatz, H. Anke
      J. Nat. Prod. 2012, 75, 1983-1986.

77. (2E,4R,5R,6S)-2-(4,5,6-Trihydroxycyclohex-2-en-1-ylidene)acetonitrile
       A. N. Guedem, L. P. Sandjo, T. Opatz, D. Schollmeyer and B. T. Ngadjui
       Acta Cryst. 2012, E68, o2737.

76. A Five-Step Synthesis of (±)-Tylophorine via a Nitrile-stabilized Ammonium Ylide
     
G. Lahm, A. Stoye, T. Opatz
      J. Org. Chem. 2012, 77, 6620-6623.

75. Screening of ligands for the Ullmann synthesis of electron rich diaryl ethers
      
N. Otto, T. Opatz
       Beilstein J. Org. Chem. 2012, 8, 1105-1111.

74. Phenguignardic Acid and Guignardic Acid, Phytotoxic Secondary Metabolites from
      Guignardia bidwellii
     
D. Molitor, J. C. Liermann, B. Berkelmann-Löhnertz, I. Buckel, T. Opatz, E. Thines
      J. Nat. Prod. 2012, 75, 1265-1269.

73. Isolactarane and Sterpurane Sesquiterpenoids from the Basidiomycete Phlebia uda
     
A. Schüffler, B. Wollinsky, T. Anke, J. C. Liermann, T. Opatz
      J. Nat. Prod. 2012, 75, 1405-1408.

72. Gems from traditional north-African medicine: medicinal and aromatic plants from
      Sudan
     
H. Khalid, W. E. Abdalla, H. Abdelgadir, T. Opatz, T. Efferth
      Nat. Prod. Bioprospect. 2012, 2, 92-103.

71. A Modular Synthesis of Polysubstituted Indolizines    
     
M. Kücükdisli, T. Opatz    
     
Eur. J. Org. Chem. 2012, 4555-4564.

70. 3'-Demethyldihydromaldoxin and Dihydromaldoxin, two anti-inflammtorydiaryl ethers
      from a Steganospora species  
     
G. Erkel, D. Schreiber, M. Jung, L. P. Sandjo, J. C. Liermann, T. Opatz   
      J. Antibiot. 2012, 65, 473-477.

69. Donellanic acids A–C: new cyclopropanic oleanane derivatives from Donella   
      ubanguiensis (Sapotaceae)     
     
A. V. B. Djoumessi, L. P. Sandjo, J. C. Liermann, D. Schollmeyer,V. Kuete, V. Rincheval,
      A. M. Berhanue, S. O. Yeboah, P. Wafo, B. T.Ngadjui, T. Opatz     
      Tetrahedron 2012, 68(24), 4621-4627.

68. Coumarin derivatives from Pedilanthus tithymaloides as inhibitors of conidial
      germination in Magnaporthe oryzae
    
  L. P. Sandjo, A. J. Foster, J. Rheinheimer, H. Anke, T. Opatz, E. Thines
      Tetrahedron 2012, 53(17), 2153-2156.

67. Unexpected Formation of a 1,2-Dichloroacenaphthylene in a Friedel-Crafts Reaction
      with Chloral Hydrate
     
S. Schwolow, D. Schollmeyer, T. Opatz
      Z. Naturforsch. B 2012, 67, 272-274.

66. Synthesis of 1,3- and 2,3- Diglycosylated Indoles as Potential Trisaccharide Mimetics    
       C. Wiebe, S. Fusté de la Sotilla, T. Opatz
       Synthesis 2012, 44, 1385-1397.

65. The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide     
       excision repair-deficient cells

       R. Abbasi, T. Efferth, C. Kuhmann, T. Opatz, X. Hao, O. Popanda, P. Schmezer
      Toxicol. Appl. Pharmacol. 2012, 259(3), 302-310 .

64. Monosaccharidic Mimetics of the Sialyl Lewis X Tetrasaccharide basedon    
      2,7-Dihydroxynaphthalene

      S. Weck, M. Frank, A. Hamann, T. Opatz
      ARKIVOC 2012 (iii), 134-148.

63. Microwave-Assisted Synthesis of 1,3-Disubstituted β-Carbolines from
       α-(Alkylideneamino)nitriles
and Gramine
      J. Letessier, H. Detert, K. Götz, T. Opatz
      Synthesis 2012, 747-754.

62. GKK1032A2, a secondary metabolite from Penicillium sp. IBWF-029-96, inhibits
       conidial germination in the rice blast fungus Magnaporthe oryzae

       J. Becker, J. C. Liermann, T. Opatz, H. Anke, E. Thines
       J. Antibiot. 2012, 65, 99-102.


2011


61. (rac)-4-[(E)-{[1-Cyano-1-cyclohexyl-2-(1H-indol-3-yl)ethyl]imino}methyl]benzonitrile
      J. Letessier, D. Schollmeyer, H. Detert, T. Opatz 
     Acta Cryst. 2011, E67, o3435.

60. Enantioselective Synthesis of Tetrahydroprotoberberines and
      Bisbenzylisoquinoline Alkaloids from a Deprotonated alpha-Aminonitrile

      N. Blank, T. Opatz
      J. Org. Chem. 2011, 76, 9777-9784.

59. 1,3-Benzyl Migration in Iminium Ions – Evidence for a Fast Free Radical Chain
       Reaction

       N. Blank, B. F. Straub, T. Opatz
       Eur. J. Org. Chem. 2011, 7355-7365.

58. Ganodermycin, a Novel Inhibitor of CXCL10 Expression from Ganoderma applanatum
      G. Erkel, M. Jung, J. C. Liermann, T. Opatz
      J. Antibiot. 2011, 64, 683-686.

57. Sweet (hetero)aromatics: glycosylated templates for the construction of saccharide
       mimetics
 
       C. Wiebe, C. Schlemmer, S.Weck, T. Opatz
       Chem. Comm. 2011, 47, 9212-9214.

56. Pyrroles and Indolizidines from Deprotonated α-(Alkylideneamino)nitriles
      I. Schäfer, T. Opatz
      Synthesis 2011, 1691-1704.

55. Elucidation of the Biosynthesis and Degradation of Allantofuranone by
      Isotopic Labelling and Fermentation of Modified Precursors

     A. Schüffler, J. C. Liermann, T. Opatz, T. Anke
     ChemBioChem. 2011, 148-154. 


2010


54. N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide
      [(S,S)-TsDPEN]

      C. Schlemmer, D. Schollmeyer, N. Blank, A. Stoye, T. Opatz
      Acta Cryst. 2010, E66, o3343.

53. Microwave-Assisted Synthesis of Polysubstituted 4-Quinolones from Deprotonated
      α-Aminonitriles

      A. Romek, T. Opatz
     Eur. J. Org. Chem. 2010, 30, 5841-5849.

52 Synthesis of Bioactive 2-Aza Analogues of Ipecac and Alangium Alkaloids      
      M. Kölzer, K. Weitzel, H. U. Göringer, E. Thines, T. Opatz      
     
ChemMedChem. 2010, 5, 1456-1464.

51. Racemization-Free Synthesis of (S)-(+)-Tylophorine from L-Proline
      A. Stoye, T. Opatz
      Org. Lett. 2010, 12, 2140-2141.
      Synfacts 2010, 979.

50. β-Selective C-Mannosylation of electron rich Phenols
      S. Weck, T. Opatz
      Synthesis 2010, 14, 2393-2398.

49. Hirsutane-Type Sesquiterpenes with Uncommon Modifications from Three
      Basidiomycetes

      J. C. Liermann, A. Schüffler, B. Wollinsky, J. Birnbacher, H. Kolshorn, T. Anke, T. Opatz
      J. Org. Chem. 2010, 75, 2955-2961.

48. Caripyrin, a new inhibitor of infection-related morphogenesis in the rice
       blast fungus Magnaporthe oryzae

       P. H. Rieger, J. C. Liermann, T. Opatz, H. Anke, E. Thines
      J. Antibiot. 2010, 63, 285-289.

47. Structure Elucidation of Hypocreolide A by Enantioselective Total Synthesis
       K. Götz, J. C. Liermann, E. Thines, H. Anke, T. Opatz
      Org. Biomol. Chem. 2010, 2123-2130. 


2009


46. Z-Amino(2-methyl-3-oxoisoindolin-1-ylidene)acetonitrile
      D. Schollmeyer, D. Ferenc, T. Opatz
      Acta Cryst. 2009, E65, o3024.

45. Xanthepinone, an Antimicrobial Polyketide from a Soil Fungus Closely
       Related to Phoma medicaginis

      J. C. Liermann, H. Kolshorn, T. Opatz, E. Thines, H. Anke
      J. Nat. Prod. 2009, 72, 1905-1907.

44. Cyclocondensation of α-Aminonitriles and Enones – a Short Access to 3,4-
       Dihydro-2H-pyrrole 2-carbonitriles and 2,3,5-Trisubstituted Pyrroles

       I. Bergner, C. Wiebe, N. Meyer, T. Opatz
      J. Org. Chem. 2009, 74, 8243-8253.

43. Sfp-type 4’-phosphopantetheinyl transferase is indispensable for fungal
      pathogenicity

      R. Horbach, A. Graf, F. Weihmann, L. Antelo, S. Mathea, J. C. Liermann, T. Opatz, E. Thines, J.
     Aguirre, H. B. Deising
     Plant Cell 2009, 21, 3379-3396.

42. New caloporoside derivatives and their inhibition of fungal spore germination
      A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, T. Anke 
     Z. Naturforsch. C 2009, 64, 521-525.

41. Isolation, structure elucidation and biological evaluation of the unusual
       heterodimer chrysoxanthone from the ascomycete IBWF11-95A

      A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, H. Anke
      Tetrahedron Lett. 2009, 50, 4813-4815.

40. Anthranicine, an Unusual Cyclic Hexapeptide from Acremonium sp. A29-2004
      J. C. Liermann, E. Thines, H. Anke, T. Opatz
      Z. Naturforsch. B 2009, 64, 727-730.

39. The Chemistry of Deprotonated α-Aminonitriles (Review)
       T. Opatz
       Synthesis 2009, 1941-1959. 

38. Omphalotins E-I, Five Oxidatively Modified Nematicidal Cyclopeptides
       from Omphalotus olearius

       J. C. Liermann, T. Opatz, H. Kolshorn, L. Antelo, C. Hof, H. Anke
      Eur. J. Org. Chem. 2009, 1256-1262.

37. Allantofuranone, a New Antifungal Antibiotic from Allantophomopsis
       lycopodina IBWF58B-05A

       A. Schüffler, D. Kautz, J. C. Liermann, T. Opatz, T. Anke
      J. Antibiot. 2009, 62, 119-121.

36. New Naphthoquinone Derivatives from the Ascomycete IBWF79B-90A
      A. Schüffler, J. C. Liermann, H. Kolshorn, T. Opatz, H. Anke
      Z. Naturforsch. C 2009, 64, 25-31.

35. Modular Synthesis of Tetrasubstituted Imidazoles and Trisubstituted
      Oxazoles by Aldimine Cross Coupling

      C. Kison, T. Opatz
      Chem. Eur. J. 2009, 15, 843-845.
      Synfacts 2009, 377.


2008


34. Ascomycones
      T. Opatz, H. Kolshorn, E. Thines, H. Anke
     J. Nat. Prod. 2008, 71, 1973-197.

33. Synthesis of the CDK-Inhibitor Paullone by Cyclization of a Deprotonated
      α-Aminonitrile
      T. Opatz, D. Ferenc
      Synthesis 2008, 3941-3944.

32. Sterelactones: new isolactarane type sesquiterpenoids with antifungal
       activity from Stereum sp. IBWF 01060

       T. Opatz, H. Kolshorn, H. Anke
       J. Antibiot. 2008, 61, 563-567.

31. Tetracyclic Terpenoids from Dasyscyphus niveus, Dasyscyphins D and E
       J. C. Liermann, H. Kolshorn, H. Anke, E. Thines, T. Opatz
      J. Nat. Prod. 2008, 71, 1654-1656.

30. Synthesis of Lamellarin U and Lamellarin G Trimethyl Ether by
      Alkylation of a Deprotonated α-Aminonitrile

      J. C. Liermann, T. Opatz
      J. Org. Chem. 2008, 73, 4526-4531.

29. Oxacyclododecindione, a novel inhibitor of IL-4 signaling from
       Exserohilum rostratum

       G. Erkel, H. Belahmer, A. Serwe, T. Anke, H. Kunz, H. Kolshorn, J. Liermann, T. Opatz
       J. Antibiot. 2008, 61, 285-290.

28. Isolation and biological activity of new norhirsutanes from Creolophus
      cirrhatus

      J. Birnbacher, A. Schueffler, F. Deininger, T. Opatz, T. Anke
      Z. Naturforsch. C 2008, 63, 203-206.

27. One-pot synthesis of trisubstituted 1,2-amino alcohols from deprotonated
      α-amino nitriles

      C. Kison, T. Opatz
      Eur. J. Org. Chem. 2008, 2740-2745.


2007


26. The creolophins: a family of linear triquinanes from Creolophus cirrhatus
       (basidiomycete)

       T. Opatz, H. Kolshorn, J. Birnbacher, A. Schuffler, F. Deininger, T. Anke
       Eur. J. Org. Chem. 2007, 5546-5550.

25. A Modular One-Pot Synthesis of Tetrasubstituted Pyrroles from
      α-
(Alkylideneamino)nitriles
       I. Bergner, T. Opatz
      J. Org. Chem. 2007, 72, 7083-7090.

24. Synthesis of (-)-(S)-Norlaudanosine, (+)-(R)-O,O-Dimethylcoclaurine, and
      (+)-(R)-Salsolidine by Alkylation of an α-Aminonitrile

      F. Werner, N. Blank, T. Opatz
      Eur. J. Org. Chem. 2007, 3911-3915.

23. Synthesis of γ-Amino Acid Esters via 1,4-Addition of Deprotonated α-
      Aminonitriles and α-(Alkylideneamino)nitriles to α,β-Unsaturated Esters

      I. Bergner, T. Opatz
     Synthesis 2007, 918-928.


2006


22. Preparation of indoles from α-aminonitriles: a short synthesis of FGIN-1-27
      T. Opatz, D. Ferenc
      Org. Lett. 2006, 8, 4473-447.

21. Synthesis of Highly Substituted Unsymmetrical 1,2-Diamines, 1,2-
       Diimines, Imidazolium Salts and Imidazolylidenes by Aldimine Cross-Coupling
       C. Kison, T. Opatz
      Synthesis 2006, 3727-3738.

20. One-pot synthesis of (±)-crispine A and its C-ring-substituted analogs
       N. Meyer, T. Opatz
      Eur. J. Org. Chem. 2006, 3997-4002.

19. Ring contracting rearrangements of 3-amino-4-(arylamino)-1H-isochromen-1-ones
      T. Opatz, D. Ferenc
      Eur. J. Org. Chem. 2006, 121-126.


2005


18. An Aldimine Cross-Coupling for the Diastereoselective Synthesis of
       Unsymmetrical 1,2-Diamines

       C. Kison, N. Meyer, T. Opatz
      Angew. Chem., Int. Ed. 2005, 44, 5662-5664.

17. One-pot Synthesis of Polysubstituted Pyrrolidines from Aminonitriles
       N. Meyer, F. Werner, T. Opatz
      Synthesis 2005, 945-956.

16. Facile preparation of 3-amino-4-(arylamino)-1H-isochromen-1-ones by a
      new multicomponent reaction

      T. Opatz, D. Ferenc
      Eur. J. Org. Chem. 2005, 817-821.


2004


15. An unexpected three-component condensation leading to amino-(3-oxo-
      2,3-dihydro-1H-isoindol-1-ylidene)-acetonitriles

      T. Opatz, D. Ferenc
      J. Org. Chem. 2004, 69, 8496-8499.

14. Synthesis of two Conformationally Restricted Piperazine Scaffolds for
      Combinatorial Chemistry

      T. Opatz
      Eur. J. Org. Chem. 2004, 4113-4118.

13. Combinatorial synthesis of amino acid- and peptide-carbohydrate
       conjugates on solid phase

       T. Opatz, C. Kallus, T. Wunberg, H. Kunz
       Tetrahedron 2004, 60, 8613-8626.

12. A short synthesis of polysubstituted pyrrolidines via α-
      (akylideneamino)nitriles

      N. Meyer, T. Opatz
      Synlett 2004, 787-790.


Ältere Publikationen


11. Addition of α-aminonitriles to α,β-unsaturated carbonyl compounds: A
      one-pot synthesis of polysubstituted pyrrolidines

      N. Meyer, T. Opatz
     Synlett 2003, 1427-1430.

10. D-Glucose as a pentavalent chiral scaffold
      T. Opatz, C. Kallus, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
      Eur. J. Org. Chem. 2003, 1527-1536.

09. D-glucose as a multivalent chiral scaffold for combinatorial chemistry

      T. Opatz, C. Kallus, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
      Carbohydr. Res. 2002, 3372089-2110.
    
08. Synthesis and screening of libraries of synthetic tripodal receptor
      molecules with three different amino acid or peptide arms: Identification

      of iron binders
      T. Opatz, R. M. J. Liskamp
      J. Comb. Chem. 2002, 4, 275-284.

07. A selectively deprotectable triazacyclophane scaffold for the construction
      of artificial receptors

      T. Opatz, R. M. J. Liskamp
      Org. Lett. 2001, 3, 3499-3502.

06. A facile cleavage of allyl ethers on solid phase
      T. Opatz, H. Kunz
      Tetrahedron Lett. 2000, 41, 10185-10188.

05. Combinatorial solid-phase synthesis using D-Galactose as a chiral five-
      dimension-diversity scaffold

      C. Kallus, T. Opatz, T. Wunberg, W. Schmidt, S. Henke, H. Kunz
      Tetrahedron Lett. 1999, 40, 7783-7786.

04. Substituted tetrahydropyrane derivatives, method for producing same,
       their use as medicine or diagnostic agent, as well as medicine containing

       same
       S. Henke, H. Kunz, T. Opatz, T. Wunberg, C. Kallus, W. Schmidt
       PCT Int. Appl. 1999,
WO9907718.

03. Carbohydrates as multifunctional chiral scaffolds in combinatorial
       synthesis

       T. Wunberg, C. Kallus, T. Opatz, S. Henke, W. Schmidt, H. Kunz
       Angew. Chem., Int. Ed. 1998, 37, 2503-2505.

02. New ventures in the construction of complex heterocycles: Synthesis of
      morphine and hasubanan alkaloids

      D. Trauner, S. Porth, T. Opatz, J. W. Bats, G. Giester, J. Mulzer
      Synthesis 1998, 653-664.
     
01. The phenanthrenone approach to opium alkaloids: Formal total synthesis
       of morphine by sigmatropic rearrangement

      J. Mulzer, J. W. Bats, B. List, T. Opatz, D. Trauner
      Synlett 1997, 441-444.  

Buchbesprechungen, Tagungsberichte


04. Quaternary Stereocenters - Challenges and Solutions for Organic Synthesis
      Herausgegeben von J. Christoffers, A. Baro
      T. Opatz
      Adv. Synth. Catal. 2006, 348, 593.

03. Glycoscience
      Herausgegeben von Bertram Fraser-Reid, Kuniaki Tatsuta und Joachim Thiem.
      T. Opatz, H. Kunz
      Angew. Chem. 2003, 115, 23.

02. Handbook of Combinatorial Chemistry - Drugs, Catalysts, Materials
       Herausgegeben von K. C. Nicolaou, R. Hanko und W. Hartwig.
       H. Kunz, T. Opatz
      J. Chem. Soc., Perkin Trans. 1, 2002, 2730.

01. Bürgenstock: Stereochemie ohne Grenzen
      R. Haag, T. Opatz
     Nachr. Chem. 2002, 50, 830-834.